Publications
Peer-Reviewed Research
Siewiera J, McIntyre TI, Cautivo KM, Mahiddine M, Rideaux D, Molofsky AB, Erlebacher A. Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity. Immunity. 2023 Jan 24;S1074-7613(23)00015-8.
Rizzuto G, Brooks JF, Tuomivaara ST, McIntyre TI, Ma S, Rideaux D, Zikherman J, Fisher SJ and Erlebacher A. Establishment of fetomaternal tolerance through glycan-mediated B cell suppression. Nature. 2022;603(7901): 497-502.
Osokine I, Siewiera J, Rideaux D, Ma S, Tsukui T, and Erlebacher A. Gene silencing by EZH2 suppresses TGF-b activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface. Cell Reports. 2022; 38(5):110329.
Mahiddine K, Blaisdell A, Ma S, Créquer-Grandhomme A, Lowell CA, Erlebacher A. Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. J Clin Invest. 2020 Jan 2;130(1):389-403.
Nancy P, Siewiera J, Rizzuto G, Tagliani E, Osokine I, Manandhar P, Dolgalev I, Clementi C, Tsirigos A, Erlebacher A. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition. J Clin Invest. 2018 Jan 2;128(1):233-247.
Rizzuto G, Tagliani E, Manandhar P, Erlebacher A, Bakardjiev AI. Limited Colonization Undermined by Inadequate Early Immune Responses Defines the Dynamics of Decidual Listeriosis. Infect Immun. 2017 Jul 19;85(8):e00153-17.
Blaisdell A, Crequer A, Columbus D, Daikoku T, Mittal K, Dey SK, Erlebacher A. Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells. Cancer Cell. 2015 Dec 14;28(6):785-799.
Tay CS, Tagliani E, Collins MK, Erlebacher A. Cis-acting pathways selectively enforce the non-immunogenicity of shed placental antigen for maternal CD8 T cells. PLoS One. 2013 Dec 31;8(12)
Nancy P, Tagliani E, Tay CS, Asp P, Levy DE, Erlebacher A. Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface. Science. 2012 Jun 8;336(6086):1317-21.
Tagliani E, Shi C, Nancy P, Tay CS, Pamer EG, Erlebacher A. Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med. 2011 Aug 29;208(9):1901-16.
Gaziel-Sovran A, Segura MF, Di Micco R, Collins MK, Hanniford D, Vega-Saenz de Miera E, Rakus JF, Dankert JF, Shang S, Kerbel RS, Bhardwaj N, Shao Y, Darvishian F, Zavadil J, Erlebacher A, Mahal LK, Osman I, Hernando E. miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer Cell. 2011 Jul 12;20(1):104-18.
McCloskey ML, Curotto de Lafaille MA, Carroll MC, Erlebacher A. Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells. J Exp Med. 2011 Jan 17;208(1):135-48.
Collins MK, Tay CS, Erlebacher A. Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice. J Clin Invest. 2009 Jul;119(7):2062-73.
Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J Clin Invest. 2007 May;117(5):1399-411.
Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. J Clin Invest. 2006 Oct;116(10):2643-52.
Tayade C, Fang Y, Black GP, V A P Jr, Erlebacher A, Croy BA. Differential transcription of Eomes and T-bet during maturation of mouse uterine natural killer cells. J Leukoc Biol. 2005 Dec;78(6):1347-55.
Erlebacher A, Price KA, Glimcher LH. Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. Dev Biol. 2004 Nov 1;275(1):158-69.
Erlebacher A, Zhang D, Parlow AF, Glimcher LH. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system. J Clin Invest. 2004 Jul;114(1):39-48.
Erlebacher A, Lukens AK, Glimcher LH. Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16940-5.
Review Articles and Book Chapters
Rizzuto G and Erlebacher A. Trophoblast antigens, fetal blood cell antigens, and the paradox of fetomaternal tolerance. J. Exp. Med. 2022. In press.
Rizzuto, G. and Erlebacher A. Maternal-Fetal Immunology. In: William Paul’s Fundamental Immunology, 8th edition. M. Flajnik, S. Holland, and N. Singh, eds. In press.
Osokine I, Erlebacher A. Inflammation and Autism: From Maternal Gut to Fetal Brain. Trends Mol Med. 2017 Dec;23(12):1070-1071.
PrabhuDas M, Bonney E, Caron K, Dey S, Erlebacher A, Fazleabas A, Fisher S, Golos T, Matzuk M, McCune JM, Mor G, Schulz L, Soares M, Spencer T, Strominger J, Way SS, Yoshinaga K. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nat Immunol. 2015 Apr;16(4):328-34.
Nancy P, Erlebacher A. T cell behavior at the maternal-fetal interface. Int J Dev Biol. 2014; 58(2-4):189-98.
Erlebacher A. Immunology of the maternal-fetal interface. Annu Rev Immunol. 2013;31:387-411.
Erlebacher A. Mechanisms of T cell tolerance towards the allogeneic fetus. Nat Rev Immunol. 2013 Jan;13(1):23-33.
Erlebacher A. Strangers no more: uterine NK cell recognition of the placenta in mice. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4267-8.
Tagliani E, Erlebacher A. Dendritic cell function at the maternal-fetal interface. Expert Rev Clin Immunol. 2011 Sep;7(5):593-602.
Erlebacher A. Immune surveillance of the maternal/fetal interface: controversies and implications. Trends Endocrinol Metab. 2010 Jul;21(7):428-34.
Thadani PV, Strauss JF 3rd, Dey SK, Anderson VM, Audus KL, Coats KS, Cross JC, Erlebacher A, Ganapathy V, Linzer DI, Miller RK, Novak DA, Rapaka RS, Sadovsky Y, Salafia CM, Soares M, Unadkat J. National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development. Am J Obstet Gynecol. 2004 Dec;191(6):1858-62.
Complete Pubmed Publications: